Simone van Breda
Field of interest: Genetic and nutritional toxicology
Simone van Breda was born on January 2nd 1977 in Hulsberg, The Netherlands. She studied Environmental Health Sciences at the Faculty of Health Sciences at Maastricht University from 1995-2000. During this period she worked as a student-researcher at the Department of Health Risk Analysis and Toxicology. From 2000-2004 she performed her PhD project at the department of Health Risk Analysis and Toxicology entitled ‘Vegetable induced gene expression changes in anticarcinogenic pathways in human and mouse tissues’ (defended December 2004). After her PhD, she received a fellowship “Talent for the Future” from the Faculty of Health Sciences, to work as a postdoctoral fellow for a period of ten months. During this appointment, she has worked at the Human Nutrition Research Centre at the lab of Prof.dr. J.C. Mathers, Newcastle upon Tyne, United Kingdom. Next, Simone was appointed as a postdoctoral fellow within an EU financed project on Environmental Carcinogenesis, Nutrition and Individual Susceptibility (ECNIS) to perform high through put analysis of genetic polymorphisms relevant to the aetiology of cancer within the framework of the Netherlands Cohort Study on Diet and Cancer (NLCS). Currently, she is works as a postdoctoral fellow supported by the EU Sixth Framework Integrated Project Newborns and Genotoxic exposure risks (NewGeneris); and, by the Transnational University Limburg (Tul). Present Research Activities: 1) Writing research projects focussing on chemoprevention in the gastrointestinal tract; 2) Investigating the molecular pathways involved in blueberry juice induced chemopreventive effects, by studying gene expression modulation in relation to the markers of antioxidant action; 3) Assessing and validating the intake of chemical compounds using questionnaire data within the Newgeneris project; 4) High throughput analyses of genetic polymorphisms using nail DNA; 5) Studying the effect of vegetables on gene expression changes in relation to changes in biomarkers of risk; 6) Examining the role of epigenetic mechanisms in gene expression changes by chemopreventive compounds. Since December 2008, Simone is registered as a toxicologist by the Netherlands Society of Toxicology and by the Federation of European Toxicologists & European Societies of Toxicology (Eurotox). Her main hobbies are diving, sports (tennis, spinning and running), nature, photography, reading and cooking.
Simone van Breda has several teaching activities within both the bachelor and master(s) of Molecular Health Sciences, including practical trainings in basic laboratory skills (1.1 Life in the biosphere, and 1.2 Macromoleculen), writing skills (STO1.1 and STO2.4), tutorial roles (1.2 Macromoleculen, 1.3 van gen tot individu, and 3.1 zieke cellen), lectures (3.4 gen, metabolisme en omgeving, 4.1 Molecular mechanisms in health and disease), journal clubs (3.4 gen, metabolisme en omgeving), and supervising students during internships (bachelor: major period; master: junior and senior internships). Furthermore, she coordinates and supervises the practical training “comet assay” within the bachelor study Health Sciences (2.5.6 veroudering).