Department of Toxicogenomics


  1. Baken KA, Pennings JLA, Breit TM, de Vries A, van Steeg H, van Loveren H. Gene expression profiling of bis(tri-n-butyltin)oxide (TBTO) induced immunotoxicity in mice and rats.. Journal of Immunotoxicology 2006;3(4): 227-244.
  2. Cauwenberghs,-S; Feijge,-M-A; Hageman,-G; Hoylaerts,-M; Akkerman,-J-W; Curvers,-J; Heemskerk,-J-W
  3. Plasma ectonucleotidases prevent desensitization of purinergic receptors in stored platelets: importance for platelet activity during thrombus formation. Transfusion. 2006 Jun; 46(6): 1018-28
  4. Corvi R, Ahr H, Albertini S, Blakey DH, Clerici L, Coecke S, Douglas GR, Gribaldo L, Groten JP, Haase B, Hamernik K, Hartung T, Inoue T, Indans I, Maurici D, Orphanides G, Rembges D, Sansone S, Snape JR, Toda E, Tong W, Delft JH, Weis B, and Schechtman LM. Validation of Toxicogenomics-Based Test Systems: ECVAM-ICCVAM/NICEATM Considerations for Regulatory Use. Environ. Health Perspect, 2006;114(3):420-9.
  5. Ezendam J, van Loveren H. Probiotics: immunomodulation and evaluation of safety and efficacy. Nutr Rev. 2006 Jan;64(1):1-14. Review.
  6. Hendriksen PJM, Dits NFJ, Veldhoven A, van Weerden WM, Bangma CH, Trapman J, Jenster G. Evolution of the androgen receptor pathway during progression of prostate cancer. Cancer Research 2006. 66:5012-5020.
  7. Ketelslegers HB, Gottschalk RW, Godschalk RW, Knaapen AM, van Schooten FJ, Vlietinck RF, Kleinjans JC, van Delft JH. Interindividual variations in DNA adduct levels assessed by analysis of multiple genetic polymorphisms in smokers. Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):624-9.
  8. Klis FM, Boorsma A, De Groot PW. Cell wall construction in Saccharomyces cerevisiae. Yeast. 2006 Feb;23(3):185-202. Review.
  9. de Kok T.C.M.C., Driece H., Hogervorst J.G.F. Briedé J.J. Toxicological risk evaluation of ambient and traffic-related particulate matter (review). Mutation Research 613 (2006) 103-22
  10. Langie S.A.S., Knaapen A.M., Brauers K.J.J., Van Schooten FJ, Godschalk R.W.L. A modified Comet Assay to phenotypically assess inter-individual variations in nucleotide excision repair. Mutagenesis vol. 21 no. 2 pp. 153–158, 2006.
  11. Langie SA, Knaapen AM, Brauers KJ, van Berlo D, van Schooten FJ, Godschalk RW. Development and validation of a modified comet assay to phenotypically assess nucleotide excision repair. Mutagenesis. 2006 Mar; 21(2):153-8.
  12. Langie SA, Knaapen AM, Houben JM, van Kempen FC, de Hoon JP, Gottschalk RW, Godschalk RW, van Schooten FJ. The role of glutathione in the regulation of nucleotide excision repair during oxidative stress. Toxicol Lett. 2006 Nov 16.
  13. Sarrif A, Kyrtopoulos SA, Autrup H, Farmer P, Kirsch-Volders M, Kleinjans JC, Knudsen LE, Mathar U, Wiegand HJ, Vrijhof H. Environmental genotoxins in children and adults: introduction and overview. Mutat Res. 2006 Sep 28;608(2):97-9. Epub 2006 Jul 11. No abstract available. Letter to the Editor
  14. Steerenberg PA, Daamen F, Weesendorp E, Van Loveren H. No adaptation to UV-induced immuno suppression and DNA damage following exposure of mice to chronic UV-exposure. J Photochem Photobiol B. 2006 Jul 3;84(1):28-37. Epub 2006 Feb 28.
  15. van der Heul-Nieuwenhuijsen L, Hendriksen PJM, van der Kwast TH, Jenster G. (2006). Gene expression profiling of the human prostate zones. BJU Int 98:886-97.
  16. van Leeuwen DM, van Agen E, Gottschalk RW, Vlietinck R, Gielen M, van Herwijnen MH, Maas LM, Kleinjans JC, van Delft JH. Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs. Carcinogenesis. 2006 Oct 19.
  17. van Schayck CP, Hogervorst JG, de Kok TM, Briede JJ, Wesseling G, Kleinjans JCS. Relationship between the composition of fine dust particles in the air and lung function in school children. Ned Tijdschr Geneeskd. 2006 Apr 1;150(13):735-40.