2018

• Mannaerts D,Faes E,Cos P,Briedé JJ,Gyselaers W,Cornette J,Gorbanev Y,Bogaerts A,Spaanderman M,Van Craenenbroeck E,Jacquemyn Y Oxidative stress in healthy pregnancy and preeclampsia is linked to chronic inflammation, iron status and vascular function. PloS one; 2018 30204759,10.1371/journal.pone.0202919,PONE-D-18-04171,PMC6133366
• Espín-Pérez A,Portier C,Chadeau-Hyam M,van Veldhoven K,Kleinjans JCS,de Kok TMCM Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data. PloS one; 2018 30161168,10.1371/journal.pone.0202947,PONE-D-17-28332,PMC6117018
• Proquin H,Rodríguez-Ibarra C,Moonen C,Urrutia Ortega IM,Briedé JJ,de Kok TM,van Loveren H,Irasema Chirino Y Titanium dioxide food additive (E171) induces ROS formation and genotoxicity: contribution of micro and nano-sized fractions. Mutagenesis; 2018 Sep 30107553,5071787,10.1093/mutage/gey011
• Mostafavi N,Vermeulen R,Ghantous A,Hoek G,Probst-Hensch N,Herceg Z,Tarallo S,Naccarati A,Kleinjans JCS,Imboden M,Jeong A,Morley D,Amaral AFS,van Nunen E,Gulliver J,Chadeau-Hyam M,Vineis P,Vlaanderen J Acute changes in DNA methylation in relation to 24 h personal air pollution exposure measurements: A panel study in four European countries. Environment international; 2018 Nov 30055357,S0160-4120(18)30560-9,10.1016/j.envint.2018.07.026
• Ward MH,Jones RR,Brender JD,de Kok TM,Weyer PJ,Nolan BT,Villanueva CM,van Breda SG Drinking Water Nitrate and Human Health: An Updated Review. International journal of environmental research and public health; 2018 Jul 30041450,ijerph15071557,10.3390/ijerph15071557,PMC6068531
• Berger E,Delpierre C,Hosnijeh FS,Kelly-Irving M,Portengen L,Bergdahl IA,Johansson AS,Krogh V,Palli D,Panico S,Sacerdote C,Tumino R,Kyrtopoulos SA,Vineis P,Chadeau-Hyam M,Vermeulen R,Castagné R, Association between low-grade inflammation and Breast cancer and B-cell Myeloma and Non-Hodgkin Lymphoma: findings from two prospective cohorts. Scientific reports; 2018 Jul 30018397,10.1038/s41598-018-29041-1,10.1038/s41598-018-29041-1,PMC6050323
• Tareen SHK,Kutmon M,Adriaens ME,Mariman ECM,de Kok TM,Arts ICW,Evelo CT Exploring the cellular network of metabolic flexibility in the adipose tissue. Genes & nutrition; 2018 30002738,10.1186/s12263-018-0609-3,609,PMC6034334
• Espín-Pérez A,Krauskopf J,Chadeau-Hyam M,van Veldhoven K,Chung F,Cullinan P,Piepers J,van Herwijnen M,Kubesch N,Carrasco-Turigas G,Nieuwenhuijsen M,Vineis P,Kleinjans JCS,de Kok TMCM Short-term transcriptome and microRNAs responses to exposure to different air pollutants in two population studies. Environmental pollution (Barking, Essex : 1987); 2018 Nov 29980036,S0269-7491(18)30788-7,10.1016/j.envpol.2018.06.051
• Proquin H,Jetten MJ,Jonkhout MCM,Garduño-Balderas LG,Briedé JJ,de Kok TM,van Loveren H,Chirino YI Transcriptomics analysis reveals new insights in E171-induced molecular alterations in a mouse model of colon cancer. Scientific reports; 2018 Jun 29950665,10.1038/s41598-018-28063-z,10.1038/s41598-018-28063-z,PMC6021444
• Smit E,Caiment F,Piepers J,Kleinjans JCS,van den Beucken T Translational regulation is a key determinant of the cellular response to benzo[a]pyrene. Toxicology letters; 2018 Oct 29906497,S0378-4274(18)30248-0,10.1016/j.toxlet.2018.06.009
• Verheijen M,Schrooders Y,Gmuender H,Nudischer R,Clayton O,Hynes J,Niederer S,Cordes H,Kuepfer L,Kleinjans J,Caiment F Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling. Toxicology letters; 2018 Sep 29803840,S0378-4274(18)30226-1,10.1016/j.toxlet.2018.05.029
• Alexeeff SE,Roy A,Shan J,Liu X,Messier K,Apte JS,Portier C,Sidney S,Van Den Eeden SK High-resolution mapping of traffic related air pollution with Google street view cars and incidence of cardiovascular events within neighborhoods in Oakland, CA. Environmental health : a global access science source; 2018 05 29759065,10.1186/s12940-018-0382-1,10.1186/s12940-018-0382-1,PMC5952592
• Campanella G,Gunter MJ,Polidoro S,Krogh V,Palli D,Panico S,Sacerdote C,Tumino R,Fiorito G,Guarrera S,Iacoviello L,Bergdahl IA,Melin B,Lenner P,de Kok TMCM,Georgiadis P,Kleinjans JCS,Kyrtopoulos SA,Bueno-de-Mesquita HB,Lillycrop KA,May AM,Onland-Moret NC,Murray R,Riboli E,Verschuren M,Lund E,Mode N,Sandanger TM,Fiano V,Trevisan M,Matullo G,Froguel P,Elliott P,Vineis P,Chadeau-Hyam M Epigenome-wide association study of adiposity and future risk of obesity-related diseases. International journal of obesity (2005); 2018 May 29713043,10.1038/s41366-018-0064-7,10.1038/s41366-018-0064-7
• Bourguignon JP,Parent AS,Kleinjans JCS,Nawrot TS,Schoeters G,Van Larebeke N Rationale for Environmental Hygiene towards global protection of fetuses and young children from adverse lifestyle factors. Environmental health : a global access science source; 2018 04 29685149,10.1186/s12940-018-0385-y,10.1186/s12940-018-0385-y,PMC5914065
• Vermeulen R,Saberi Hosnijeh F,Bodinier B,Portengen L,Liquet B,Garrido-Manriquez J,Lokhorst H,Bergdahl IA,Kyrtopoulos SA,Johansson AS,Georgiadis P,Melin B,Palli D,Krogh V,Panico S,Sacerdote C,Tumino R,Vineis P,Castagné R,Chadeau-Hyam M, ,Botsivali M,Chatziioannou A,Valavanis I,Kleinjans JCS,de Kok TMCM,Keun HC,Athersuch TJ,Kelly R,Lenner P,Hallmans G,Stephanou EG,Myridakis A,Kogevinas M,Fazzo L,De Santis M,Comba P,Bendinelli B,Kiviranta H,Rantakokko P,Airaksinen R,Ruokojarvi P,Gilthorpe M,Fleming S,Fleming T,Tu YK,Lundh T,Chien KL,Chen WJ,Lee WC,Kate Hsiao C,Kuo PH,Hung H,Liao SF Pre-diagnostic blood immune markers, incidence and progression of B-cell lymphoma and multiple myeloma: Univariate and functionally informed multivariate analyses. International journal of cancer; 2018 Sep 29667176,10.1002/ijc.31536,PMC6100111
• Ščupáková K,Soons Z,Ertaylan G,Pierzchalski KA,Eijkel GB,Ellis SR,Greve JW,Driessen A,Verheij J,De Kok TM,Olde Damink SWM,Rensen SS,Heeren RMA Spatial Systems Lipidomics Reveals Nonalcoholic Fatty Liver Disease Heterogeneity. Analytical chemistry; 2018 Apr 29570976,10.1021/acs.analchem.7b05215,PMC5906754
• Wolters JEJ,van Breda SGJ,Grossmann J,Fortes C,Caiment F,Kleinjans JCS Integrated 'omics analysis reveals new drug-induced mitochondrial perturbations in human hepatocytes. Toxicology letters; 2018 Jun 29501571,S0378-4274(18)30072-9,10.1016/j.toxlet.2018.02.026
• de Jong HJI,Cohen Tervaert JW,Lalmohamed A,de Vries F,Vandebriel RJ,van Loveren H,Klungel OH,van Staa TP Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink. PloS one; 2018 29474418,10.1371/journal.pone.0193297,PONE-D-17-27211,PMC5825093
• Briedé JJ,Deferme L,Wolters JEJ,Claessen SMH,van den Beucken T,Wagner RJ,van Breda SG,Kleinjans JCS A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases. Toxicology in vitro : an international journal published in association with BIBRA; 2018 Apr 29432895,S0887-2333(18)30043-2,10.1016/j.tiv.2018.02.006
• Krauskopf J,Caiment F,van Veldhoven K,Chadeau-Hyam M,Sinharay R,Chung KF,Cullinan P,Collins P,Barratt B,Kelly FJ,Vermeulen R,Vineis P,de Kok TM,Kleinjans JC The human circulating miRNome reflects multiple organ disease risks in association with short-term exposure to traffic-related air pollution. Environment international; 2018 Apr 29421404,S0160-4120(17)31982-7,10.1016/j.envint.2018.01.014
• Proquin H,Jetten MJ,Jonkhout MCM,Garduño-Balderas LG,Briedé JJ,de Kok TM,Chirino YI,van Loveren H Time course gene expression data in colon of mice after exposure to food-grade E171. Data in brief; 2018 Feb 29264374,10.1016/j.dib.2017.11.067,S2352-3409(17)30663-7,PMC5726758
• Portier CJ,Clausing P Update to 'Re: Tarazona et al. (2017): glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. doi: 10.1007/s00204-017-1962-5'. Archives of toxicology; 2018 Mar 29230486,10.1007/s00204-017-2138-z,10.1007/s00204-017-2138-z
• Escrivá L,Jennen D,Caiment F,Manyes L Transcriptomic study of the toxic mechanism triggered by beauvericin in Jurkat cells. Toxicology letters; 2018 Mar 29203277,S0378-4274(17)31496-0,10.1016/j.toxlet.2017.11.035
• Wolters J,van Breda S,Claessen S,de Kok T,Kleinjans J Data on novel DNA methylation changes induced by valproic acid in human hepatocytes. Data in brief; 2018 Feb 29201983,10.1016/j.dib.2017.11.031,S2352-3409(17)30627-3,PMC5702865
• van Breda SGJ,Claessen SMH,van Herwijnen M,Theunissen DHJ,Jennen DGJ,de Kok TMCM,Kleinjans JCS Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology; 2018 01 29154799,S0300-483X(17)30343-8,10.1016/j.tox.2017.11.013
• Konings GF,Cornel KM,Xanthoulea S,Delvoux B,Skowron MA,Kooreman L,Koskimies P,Krakstad C,Salvesen HB,van Kuijk K,Schrooders YJ,Vooijs M,Groot AJ,Bongers MY,Kruitwagen RF, ,Romano A Blocking 17β-hydroxysteroid dehydrogenase type 1 in endometrial cancer: a potential novel endocrine therapeutic approach. The Journal of pathology; 2018 Feb 29144553,10.1002/path.5004
• Proquin H,Jetten MJ,Jonkhout MCM,Garduño-Balderas LG,Briedé JJ,de Kok TM,Chirino YI,van Loveren H Gene expression profiling in colon of mice exposed to food additive titanium dioxide (E171). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association; 2018 Jan 29128614,S0278-6915(17)30669-5,10.1016/j.fct.2017.11.011
• Espín-Pérez A,Font-Ribera L,van Veldhoven K,Krauskopf J,Portengen L,Chadeau-Hyam M,Vermeulen R,Grimalt JO,Villanueva CM,Vineis P,Kogevinas M,Kleinjans JC,de Kok TM Blood transcriptional and microRNA responses to short-term exposure to disinfection by-products in a swimming pool. Environment international; 2018 01 29122314,S0160-4120(17)31182-0,10.1016/j.envint.2017.10.003
• van Breda SGJ,de Kok TMCM Smart Combinations of Bioactive Compounds in Fruits and Vegetables May Guide New Strategies for Personalized Prevention of Chronic Diseases. Molecular nutrition & food research; 2018 01 29108107,10.1002/mnfr.201700597
• Kuepfer L,Clayton O,Thiel C,Cordes H,Nudischer R,Blank LM,Baier V,Heymans S,Caiment F,Roth A,Fluri DA,Kelm JM,Castell J,Selevsek N,Schlapbach R,Keun H,Hynes J,Sarkans U,Gmuender H,Herwig R,Niederer S,Schuchhardt J,Segall M,Kleinjans J A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity. Archives of toxicology; 2018 Jan 28852801,10.1007/s00204-017-2041-7,10.1007/s00204-017-2041-7,PMC5773653
• O'Callaghan-Gordo C,Kogevinas M,Pedersen M,Fthenou E,Espinosa A,Tsiapa X,Chalkiadaki G,Daraki V,Dermitzaki E,Decordier I,Farmer PB,Georgiadis P,Georgiou V,Kyrtopoulos SA,Merlo DF,Romaguera D,Roumeliotaki T,Sarri K,Törnqvist M,Loock KV,von Stedingk H,Kleinjans J,Kirsch-Volders M,Chatzi L Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete). European journal of nutrition; 2018 Feb 27655526,10.1007/s00394-016-1310-1,10.1007/s00394-016-1310-1