1. Proquin H, Jetten MJ, Jonkhout MCM, Garduño-Balderas LG, Briedé JJ, de Kok TM,Chirino YI, van Loveren H. Time course gene expression data in colon of mice after exposure to food-grade E171. Data Brief. 2017 Nov 22;16:531-600. doi: 10.1016/j.dib.2017.11.067. eCollection 2018 Feb. PubMed PMID: 29264374; PubMed Central PMCID: PMC5726758.
  2. Portier CJ, Clausing P. Update to 'Re: Tarazona et al. (2017): glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. doi: 10.1007/s00204-017-1962-5'. Arch Toxicol. 2018 Mar;92(3):1341. doi: 10.1007/s00204-017-2138-z. Epub 2017 Dec PubMed PMID: 29230486.
  3. Escrivá L, Jennen D, Caiment F, Manyes L. Transcriptomic study of the toxic mechanism triggered by beauvericin in Jurkat cells. Toxicol Lett. 2018 Mar 1;284:213-221. doi: 10.1016/j.toxlet.2017.11.035. Epub 2017 Dec 1. PubMed PMID:29203277.
  4. Wolters J, van Breda S, Claessen S, de Kok T, Kleinjans J. Data on novel DNA methylation changes induced by valproic acid in human hepatocytes. Data Brief. 2017 Nov 10;16:161-171. doi: 10.1016/j.dib.2017.11.031. eCollection 2018 Feb.PubMed PMID: 29201983; PubMed Central PMCID: PMC5702865.
  5. van Breda SGJ, Claessen SMH, van Herwijnen M, Theunissen DHJ, Jennen DGJ, de Kok TMCM, Kleinjans JCS. Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170. doi: 10.1016/j.tox.2017.11.013. Epub 2017 Nov 14. PubMed PMID: 29154799.
  6.  Proquin H, Jetten MJ, Jonkhout MCM, Garduño-Balderas LG, Briedé JJ, de Kok TM, Chirino YI, van Loveren H. Gene expression profiling in colon of mice exposed to food additive titanium dioxide (E171). Food Chem Toxicol. 2018 Jan;111:153-165. doi: 10.1016/j.fct.2017.11.011. Epub 2017 Nov 8. PubMed PMID: 29128614.
  7. Espín-Pérez A, Font-Ribera L, van Veldhoven K, Krauskopf J, Portengen L, Chadeau-Hyam M, Vermeulen R, Grimalt JO, Villanueva CM, Vineis P, Kogevinas M, Kleinjans JC, de Kok TM. Blood transcriptional and microRNA responses to short-term exposure to disinfection by-products in a swimming pool. Environ Int. 2018 Jan;110:42-50. doi: 10.1016/j.envint.2017.10.003. Epub 2017 Nov 6. PubMed PMID: 29122314.
  8. van Breda SGJ, de Kok TMCM. Smart Combinations of Bioactive Compounds in Fruits and Vegetables May Guide New Strategies for Personalized Prevention of Chronic Diseases. Mol Nutr Food Res. 2018 Jan;62(1). doi: 10.1002/mnfr.201700597. Epub 2017 Dec 19. Review. PubMed PMID: 29108107.
  9. Souza TM, Kleinjans JCS, Jennen DGJ. Dose and Time Dependencies in Stress Pathway Responses during Chemical Exposure: Novel Insights from Gene Regulatory Networks. Front Genet. 2017 Oct 6;8:142. doi: 10.3389/fgene.2017.00142. eCollection 2017. PubMed PMID: 29085386; PubMed Central PMCID: PMC5649202.
  10. Germolec D, Luebke R, Rooney A, Shipkowski K, Vandebriel R, van Loveren H. Immunotoxicology: A brief history, current status and strategies for future immunotoxicity assessment. Curr Opin Toxicol. 2017 Aug;5:55-59. PubMed PMID: 28989989; PubMed Central PMCID: PMC5629009.
  11. Buesen R, Chorley BN, da Silva Lima B, Daston G, Deferme L, Ebbels T, Gant TW, Goetz A, Greally J, Gribaldo L, Hackermüller J, Hubesch B, Jennen D, Johnson K, Kanno J, Kauffmann HM, Laffont M, McMullen P, Meehan R, Pemberton M, Perdichizzi S, Piersma AH, Sauer UG, Schmidt K, Seitz H, Sumida K, Tollefsen KE, Tong W, Tralau T, van Ravenzwaay B, Weber RJM, Worth A, Yauk C, Poole A. Applying'omics technologies in chemicals risk assessment: Report of an ECETOC workshop. Regul Toxicol Pharmacol. 2017 Dec;91 Suppl 1:S3-S13. doi: 10.1016/j.yrtph.2017.09.002. Epub 2017 Sep 25. Review. PubMed PMID: 28958911.
  12. Corvi R, Madia F, Guyton KZ, Kasper P, Rudel R, Colacci A, Kleinjans J, Jennings P. Moving forward in carcinogenicity assessment: Report of an EURL ECVAM/ESTIV workshop. Toxicol In Vitro. 2017 Dec;45(Pt 3):278-286. doi: 10.1016/j.tiv.2017.09.010. Epub 2017 Sep 12. PubMed PMID: 28911985; PubMed Central PMCID: PMC5735222.
  13. Georgiadis P, Liampa I, Hebels DG, Krauskopf J, Chatziioannou A, Valavanis I, de Kok TMCM, Kleinjans JCS, Bergdahl IA, Melin B, Spaeth F, Palli D, Vermeulen RCH, Vlaanderen J, Chadeau-Hyam M, Vineis P, Kyrtopoulos SA; EnviroGenomarkers consortium. Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis. BMC Genomics. 2017 Sep 13;18(1):728. doi: 10.1186/s12864-017-4117-4. PubMed PMID: 28903739; PubMed Central PMCID: PMC5598006.
  14. Brand W, Noorlander CW, Giannakou C, De Jong WH, Kooi MW, Park MV, Vandebriel RJ, Bosselaers IE, Scholl JH, Geertsma RE. Nanomedicinal products: a survey on specific toxicity and side effects. Int J Nanomedicine. 2017 Aug 22;12:6107-6129.doi: 10.2147/IJN.S139687. eCollection 2017. PubMed PMID: 28883724; PubMed Central PMCID: PMC5574663.
  15. Smit E, Souza T, Jennen DGJ, Kleinjans JCS, van den Beucken T. Identification of essential transcription factors for adequate DNA damage response after benzo(a)pyrene and aflatoxin B1 exposure by combining transcriptomics with functional genomics. Toxicology. 2017 Sep 1;390:74-82. doi: 10.1016/j.tox.2017.09.002. Epub 2017 Sep 4. PubMed PMID: 28882572.
  16. Wolters JEJ, van Breda SGJ, Caiment F, Claessen SM, de Kok TMCM, Kleinjans JCS. Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes. Chem Res Toxicol. 2017 Oct 16;30(10):1847-1854. doi:10.1021/acs.chemrestox.7b00171. Epub 2017 Sep 13. PubMed PMID: 28853863; PubMed Central PMCID: PMC5645762.
  17. Kuepfer L, Clayton O, Thiel C, Cordes H, Nudischer R, Blank LM, Baier V, Heymans S, Caiment F, Roth A, Fluri DA, Kelm JM, Castell J, Selevsek N, Schlapbach R, Keun H, Hynes J, Sarkans U, Gmuender H, Herwig R, Niederer S, Schuchhardt J, Segall M, Kleinjans J. A model-based assay design to reproduce in  vivo patterns of acute drug-induced toxicity. Arch Toxicol. 2018 Jan;92(1):553-555. doi: 10.1007/s00204-017-2041-7. Epub 2017 Aug 29. PubMed PMID: 28852801; PubMed Central PMCID: PMC5773653.
  18. Plusquin M, Guida F, Polidoro S, Vermeulen R, Raaschou-Nielsen O, Campanella  G, Hoek G, Kyrtopoulos SA, Georgiadis P, Naccarati A, Sacerdote C, Krogh V, Bas Bueno-de-Mesquita H, Monique Verschuren WM, Sayols-Baixeras S, Panni T, Peters A, Hebels DGAJ, Kleinjans J, Vineis P, Chadeau-Hyam M. DNA methylation and exposure  to ambient air pollution in two prospective cohorts. Environ Int. 2017 Nov;108:127-136. doi: 10.1016/j.envint.2017.08.006. Epub 2017 Aug 24. PubMed PMID: 28843141; PubMed Central PMCID: PMC6139298.
  19. Krauskopf J, de Kok TM, Hebels DG, Bergdahl IA, Johansson A, Spaeth F, Kiviranta H, Rantakokko P, Kyrtopoulos SA, Kleinjans JC. MicroRNA profile for health risk assessment: Environmental exposure to persistent organic pollutants strongly affects the human blood microRNA machinery. Sci Rep. 2017 Aug 23;7(1):9262. doi: 10.1038/s41598-017-10167-7. PubMed PMID: 28835693; PubMed Central PMCID: PMC5569060.
  20. Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JCS, Jennen DGJ, de Kok TM. The idiosyncratic drug-induced gene expression changes in HepG2 cells. Data Brief. 2017 Jul 29;14:462-468. doi: 10.1016/j.dib.2017.07.074. eCollection 2017 Oct. PubMed PMID: 28831409; PubMed Central PMCID: PMC5554930.
  21. Winckelmans E, Nawrot TS, Tsamou M, Den Hond E, Baeyens W, Kleinjans J, Lefebvre W, Van Larebeke N, Peusens M, Plusquin M, Reynders H, Schoeters G, Vanpoucke C, de Kok TM, Vrijens K. Transcriptome-wide analyses indicate mitochondrial responses to particulate air pollution exposure. Environ Health. 2017 Aug 18;16(1):87. doi: 10.1186/s12940-017-0292-7. PubMed PMID: 28821289; PubMed Central PMCID: PMC5563023.
  22. Van den Hof WFPM, Coonen MLJ, van Herwijnen M, Brauers K, Jennen D, Olde Damink SWM, Schaap FG, Kleinjans JCS. Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis. Toxicol In Vitro. 2017 Oct;44:322-329. doi: 10.1016/j.tiv.2017.07.024. Epub 2017 Aug 1. PubMed PMID: 28778767.
  23. Ertaylan G, Le Cornet C, van Roekel EH, Jung AY, Bours MJL, Damms-Machado A, van den Brandt PA, Schock H, de Kok TM, Theys J, Arts ICW, Kaaks R, Weijenberg MP, Fortner RT. A Comparative Study on the WCRF International/University of Bristol Methodology for Systematic Reviews of Mechanisms Underpinning Exposure-Cancer Associations. Cancer Epidemiol Biomarkers Prev. 2017 Nov;26(11):1583-1594. doi: 10.1158/1055-9965.EPI-17-0230. Epub 2017 Jul 28. Review. PubMed PMID: 28754794.
  24. Souza TM, van den Beucken T, Kleinjans JCS, Jennen DGJ. Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations. Toxicology. 2017 Aug 15;389:101-107. doi: 10.1016/j.tox.2017.07.008. Epub 2017 Jul 22. PubMed PMID: 28743512.
  25. Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JCS, Jennen DGJ, de Kok TM. Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury. Toxicol Appl Pharmacol. 2017 Oct 1;332:100-108. doi: 10.1016/j.taap.2017.07.014. Epub 2017 Jul 18. PubMed PMID:28733206.
  26. De Jong HJI, van Staa TP, Lalmohamed A, de Vries F, Vandebriel RJ, Van Loveren H, Klungel OH, Cohen Tervaert JW. Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study. Ann Rheum Dis. 2017 Oct;76(10):1723-1730. doi: 10.1136/annrheumdis-2016-210936. Epub 2017 Jul 6. PubMed PMID: 28684558.
  27. Portier CJ, Clausing P. Re: Tarazona et al. (2017): Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. doi: 10.1007/s00204-017-1962-5. Arch Toxicol. 2017 Sep;91(9):3195-3197. doi: 10.1007/s00204-017-2009-7. Epub 2017 Jun 15. PubMed PMID: 28620672.
  28. Winckelmans E, Vrijens K, Tsamou M, Janssen BG, Saenen ND, Roels HA, Kleinjans J, Lefebvre W, Vanpoucke C, de Kok TM, Nawrot TS. Newborn sex-specific transcriptome signatures and gestational exposure to fine particles: findings from the ENVIRONAGE birth cohort. Environ Health. 2017 Jun 5;16(1):52. doi: 10.1186/s12940-017-0264-y. PubMed PMID: 28583124; PubMed Central PMCID: PMC5458481.
  29. Apte JS, Messier KP, Gani S, Brauer M, Kirchstetter TW, Lunden MM, Marshall JD, Portier CJ, Vermeulen RCH, Hamburg SP. High-Resolution Air Pollution Mapping with Google Street View Cars: Exploiting Big Data. Environ Sci Technol. 2017 Jun 20;51(12):6999-7008. doi: 10.1021/acs.est.7b00891. Epub 2017 Jun 5. PubMed PMID: 28578585.
  30. Krauskopf J, de Kok TM, Schomaker SJ, Gosink M, Burt DA, Chandler P, Warner RL, Johnson KJ, Caiment F, Kleinjans JC, Aubrecht J. Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. PLoS One. 2017 May 17;12(5):e0177928. doi: 10.1371/journal.pone.0177928. eCollection 2017. PubMed PMID: 28545106; PubMed Central PMCID: PMC5435338.
  31. Gielis JF, Quirynen L, Briedé JJ, Roelant E, Cos P, Van Schil PEY. Pathogenetic role of endothelial nitric oxide synthase uncoupling during lung ischaemia-reperfusion injury. Eur J Cardiothorac Surg. 2017 Aug 1;52(2):256-263. doi: 10.1093/ejcts/ezx125. PubMed PMID: 28481990.
  32. Gielis JF, Beckers PAJ, Briedé JJ, Cos P, Van Schil PE. Oxidative and nitrosative stress during pulmonary ischemia-reperfusion injury: from the lab to the OR. Ann Transl Med. 2017 Mar;5(6):131. doi: 10.21037/atm.2017.03.32. Review. PubMed PMID: 28462211; PubMed Central PMCID: PMC5395487.
  33. McPartland J, Dantzker H, Portier C. Elucidating environmental dimensions of neurological disorders and disease: Understanding new tools from federal chemical testing programs. Sci Total Environ. 2017 Sep 1;593-594:634-640. doi: 10.1016/j.scitotenv.2017.03.024. Epub 2017 Mar 29. PubMed PMID: 28364604.
  34. Vlaanderen J, Leenders M, Chadeau-Hyam M, Portengen L, Kyrtopoulos SA, Bergdahl IA, Johansson AS, Hebels DD, de Kok TM, Vineis P, Vermeulen RC. Exploring the nature of prediagnostic blood transcriptome markers of chronic lymphocytic leukemia by assessing their overlap with the transcriptome at the clinical stage. BMC Genomics. 2017 Mar 20;18(1):239. doi: 10.1186/s12864-017-3627-4. PubMed PMID: 28320322; PubMed Central PMCID:PMC5360061.
  35. Chatziioannou A, Georgiadis P, Hebels DG, Liampa I, Valavanis I, Bergdahl IA, Johansson A, Palli D, Chadeau-Hyam M, Siskos AP, Keun H, Botsivali M, de Kok TM, Pérez AE, Kleinjans JC, Vineis P, Kyrtopoulos SA; EnviroGenomarkers project consortium. Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases. Sci Rep. 2017 Feb 22;7:42870. doi:10.1038/srep42870. PubMed PMID: 28225026; PubMed Central PMCID: PMC5320491.
  36. Kelly RS, Kiviranta H, Bergdahl IA, Palli D, Johansson AS, Botsivali M, Vineis P, Vermeulen R, Kyrtopoulos SA, Chadeau-Hyam M; EnviroGenoMarkers project consortium. Prediagnostic plasma concentrations of organochlorines and risk of B-cell non-Hodgkin lymphoma in envirogenomarkers: a nested case-control study.Environ Health. 2017 Feb 16;16(1):9. doi: 10.1186/s12940-017-0214-8. PubMed PMID: 28202064; PubMed Central PMCID: PMC5312563.
  37. Mostafavi N, Vlaanderen J, Portengen L, Chadeau-Hyam M, Modig L, Palli D, Bergdahl IA, Brunekreef B, Vineis P, Hebels DG, Kleinjans JC, Krogh V, Hoek G, Georgiadis P, Kyrtopoulos S, Vermeulen R. Associations Between Genome-wide Gene Expression and Ambient Nitrogen Oxides. Epidemiology. 2017 May;28(3):320-328. doi: 10.1097/EDE.0000000000000628. PubMed PMID: 28151741.
  38. Hendrickx DM, Souza T, Jennen DGJ, Kleinjans JCS. DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds. Arch Toxicol. 2017 Jun;91(6):2343-2352. doi: 10.1007/s00204-016-1922-5. Epub 2016 Dec 28. PubMed PMID: 28032149; PubMed Central PMCID: PMC5429357.
  39. Escher BI, Hackermüller J, Polte T, Scholz S, Aigner A, Altenburger R, Böhme  A, Bopp SK, Brack W, Busch W, Chadeau-Hyam M, Covaci A, Eisenträger A, Galligan JJ, Garcia-Reyero N, Hartung T, Hein M, Herberth G, Jahnke A, Kleinjans J, Klüver N, Krauss M, Lamoree M, Lehmann I, Luckenbach T, Miller GW, Müller A, Phillips DH, Reemtsma T, Rolle-Kampczyk U, Schüürmann G, Schwikowski B, Tan YM, Trump S, Walter-Rohde S, Wambaugh JF. From the exposome to mechanistic understanding of chemical-induced adverse effects. Environ Int. 2017 Feb;99:97-106. doi: 10.1016/j.envint.2016.11.029. Epub 2016 Dec 8. Review. PubMed PMID: 27939949; PubMed Central PMCID: PMC6116522.
  40. Proquin H, Rodríguez-Ibarra C, Moonen CG, Urrutia Ortega IM, Briedé JJ, de Kok TM, van Loveren H, Chirino YI. Titanium dioxide food additive (E171) induces  ROS formation and genotoxicity: contribution of micro and nano-sized fractions. Mutagenesis. 2017 Jan;32(1):139-149. doi: 10.1093/mutage/gew051. Epub 2016 Oct 27. Erratum in: Mutagenesis. 2018 Sep 17;33(3):267-268. PubMed PMID: 27789654.
  41. Souza TM, Rieswijk L, Beucken TV, Kleinjans J, Jennen D. Persistent transcriptional responses show the involvement of feed-forward control in a repeated dose toxicity study. Toxicology. 2017 Jan 15;375:58-63. doi: 10.1016/j.tox.2016.10.009. Epub 2016 Oct 17. PubMed PMID: 27765683.
  42. Vrijens K, Winckelmans E, Tsamou M, Baeyens W, De Boever P, Jennen D, de Kok TM, Den Hond E, Lefebvre W, Plusquin M, Reynders H, Schoeters G, Van Larebeke N, Vanpoucke C, Kleinjans J, Nawrot TS. Sex-Specific Associations between Particulate Matter Exposure and Gene Expression in Independent Discovery and Validation Cohorts of Middle-Aged Men and Women. Environ Health Perspect. 2017 Apr;125(4):660-669. doi: 10.1289/EHP370. Epub 2016 Oct 14. PubMed PMID: 27740511;PubMed Central PMCID: PMC5381989.
  43. Boei JJWA, Vermeulen S, Klein B, Hiemstra PS, Verhoosel RM, Jennen DGJ, Lahoz A, Gmuender H, Vrieling H. Xenobiotic metabolism in differentiated human bronchial epithelial cells. Arch Toxicol. 2017 May;91(5):2093-2105. doi: 10.1007/s00204-016-1868-7. Epub 2016 Oct 13. PubMed PMID: 27738743; PubMed Central PMCID: PMC5399058.
  44. Vineis P, Chadeau-Hyam M, Gmuender H, Gulliver J, Herceg Z, Kleinjans J, Kogevinas M, Kyrtopoulos S, Nieuwenhuijsen M, Phillips DH, Probst-Hensch N, Scalbert A, Vermeulen R, Wild CP; EXPOsOMICS Consortium. The exposome in practice: Design of the EXPOsOMICS project. Int J Hyg Environ Health. 2017 Mar;220(2 Pt A):142-151. doi: 10.1016/j.ijheh.2016.08.001. Epub 2016 Aug 19. PubMed PMID: 27576363; PubMed Central PMCID: PMC6192011.
  45. O'Callaghan-Gordo C, Kogevinas M, Fthenou E, Pedersen M, Espinosa A, Chalkiadaki G, Daraki V, Dermitzaki E, Decordier I, Georgiou V, Merlo DF,Roumeliotaki T, Vande Loock K, Kleinjans J, Kirsch-Volders M, Chatzi L. Vitamin D insufficient levels during pregnancy and micronuclei frequency in peripheral blood T lymphocytes mothers and newborns (Rhea cohort, Crete). Clin Nutr. 2017 Aug;36(4):1029-1035. doi: 10.1016/j.clnu.2016.06.016. Epub 2016 Jun 27. PubMed PMID: 27396287.
  46. Sand S, Parham F, Portier CJ, Tice RR, Krewski D. Comparison of Points of Departure for Health Risk Assessment Based on High-Throughput Screening Data. Environ Health Perspect. 2017 Apr;125(4):623-633. doi: 10.1289/EHP408. Epub 2016  Jul 6. PubMed PMID: 27384688; PubMed Central PMCID: PMC5381992.